Description:
We are seeking a highly skilled and innovative Senior Scientist to join our Applications team, focused on developing cutting-edge diagnostic tests for infectious diseases. The role emphasises metagenomics but also includes a range of sequencing and non-sequencing-based approaches. Ideal candidates will have strong experience with sequencing technologies, and a proven track record of developing end-to-end clinical diagnostic applications in either academic or industrial environments.
In this leadership position, you will manage a small, agile team to deliver prototype diagnostic assays in a fast-paced, start-up-like environment. Strong problem-solving, troubleshooting, and molecular biology skills are essential.
Requirements
Key Responsibilities:
- To research, design and prototype diagnostic assays for important infectious disease syndromes (e.g. respiratory tract infections) using the latest sequencing technologies (long and short read)
- To work with internal and external stakeholders to identify innovative approaches to simplify and reduce time and cost of metagenomic diagnostic approaches, from sample collection to result
- Work closely with experts to automate diagnostic assays, leading to cost-effective, easy to use tests
- Work closely with AMR, Informatic and Machine Learning colleagues ensure the tests provide accurate pathogen ID, AMR and relatedness results
- Engage with industry and academic experts to identify and assess promising new technologies relevant to the aims and objectives of the team
- To effectively transfer working prototype designs to verification and validation team and contribute to verification and validation experimental design
- Build and lead a small team of scientists to deliver on team objectives
Essential Knowledge, Skills, and Experience:
- A PhD in a relevant scientific discipline (e.g. molecular biology, genomics, microbiology, or a related field)
- In-depth expertise in genomics and/or metagenomics
- Strong foundation in molecular biology techniques and applications
- Demonstrated experience in laboratory operations and personnel management
- A proven track record of achievement in academic and/or industrial research settings
- Hands-on experience in the design, development, and prototyping of molecular assays, particularly in areas such as infectious diseases, oncology, human genetics, plant or food pathogens, or veterinary diagnostics
- Experience collaborating within multidisciplinary teams, with the ability to effectively communicate across scientific domains
Desirable Knowledge, Skills, and Experience:
- Background in microbiology and/or infectious diseases
- Familiarity with clinical metagenomics applications and workflows
- Foundational skills in bioinformatics, particularly in the analysis of genomic or metagenomic data
Key Attributes:
- Innovative thinker with a proactive approach to problem-solving and technology development
- Strong troubleshooting skills, with the ability to identify and resolve complex technical issues
- Highly organised, with excellent time management and prioritisation abilities
- Effective communicator with strong presentation skills and a proven track record of delivering to diverse audiences
- Demonstrated ability in technology horizon scanning and staying abreast of emerging scientific trends
- Proven leadership skills, with experience guiding teams and driving projects to successful outcomes