Description:
We are seeking a hands-on and technically adept GxP IT Systems Engineer to support Moderna’s manufacturing operations at our Harwell site. This is a highly interactive role embedded in site operations, working alongside automation engineers, QC analysts, warehouse teams, and manufacturing operators. You will serve as the critical link between IT and Operational Technology (OT), delivering robust, compliant systems performance and exceptional end-user support.
This is a dynamic opportunity for an individual contributor who thrives in complex, regulated environments and enjoys maintaining the technical backbone that drives GMP production. With exposure to modern observability, cybersecurity tooling, and the potential to work closely with Generative AI and automation systems, this position places you at the forefront of digital manufacturing in biotechnology.
Here’s What You’ll Do Your key responsibilities will be:
- Ensure compliance with GMP and data integrity standards, supporting inspections, audits, deviations, CAPAs, and SOP adherence.
- Provide Tier 1 support for manufacturing operations, responding to shop floor issues across workstations, HMIs, scanners, label printers, and Thin Clients.
- Triage and resolve IT incidents, requests, and change controls using a service-oriented mindset and SLAs.
- Manage infrastructure operations including troubleshooting of Windows servers, VMs (VMware/Hyper-V), Active Directory, DNS/DHCP, and time sync services.
- Support change execution activities in a validated GxP environment, maintaining audit trails and system states.
- Use observability tools such as Dynatrace, Splunk, and PagerDuty to monitor system health and resolve performance issues.
- Participate in endpoint protection and vulnerability management in coordination with security teams using tools like CrowdStrike.
- Maintain CMDB accuracy, system inventories, configuration baselines, and network documentation.
Your Responsibilities Will Also Include
- Provide day-to-day end-user IT support, including configuration and maintenance of laptops, mobile devices, and peripherals.
- Diagnose and resolve issues related to OS, Microsoft Office Suite, Outlook, and third-party applications.
- Maintain detailed documentation for tickets, repairs, imaging, data wiping, and asset tracking.
- Deliver a high-quality, customer-centric experience in all end-user interactions.
- Collaborate with QA, QC, Automation, Plant and Lab Engineering, and Digital Core teams to coordinate system downtime, restoration, and change advisory reviews.
- Participate in after-hours or weekend support activities as needed based on manufacturing demands.
The key Moderna Mindsets you’ll need to succeed in the role:
- “We behave like owners. The solutions we’re building go beyond any job description.” In this role, taking ownership is vital — you’ll be the bridge between IT, automation, and the GMP shop floor, managing essential systems that directly impact product delivery. Your ability to act proactively and think holistically ensures production continuity and regulatory alignment.
- “We digitize everywhere possible using the power of code to maximize our impact on patients.” As a GxP IT Systems Engineer, you’ll operate in a highly digitized environment using advanced monitoring, cybersecurity, and infrastructure automation tools. Your contribution will enable faster, smarter, and safer operations that ultimately accelerate the delivery of mRNA medicines to patients.
Education And Experience Here’s What You’ll Bring to the Table:
- Bachelor's degree in computer science, Information Technology, Industrial Engineering, physical science or related field or relevant experience.
- Minimum of 3-5 years of experience supporting IT/OT systems in manufacturing and labs.
- Experience working in a BioPharma, GxP environment
- Some experience working with virtual environment (VMware/Hyper-V) and/or cloud platform (AWS preferred)
- Some experience working with RDBMS (SQL Server or Oracle)
- Some experience working with backup/recovery systems (Acronis, Veeam, N2WS, etc.)
- Some experience working with Cybersecurity endpoint protection applications (CrowdStrike, Symantec, McAfee, Carbon Black, etc.)
- Some experience working with infrastructure tools (Dynatrace, Pager Duty, Splunk)
- Excellent Windows and Microsoft Office Suite trouble shooting skills, as well as hardware trouble shooting skills.
- Experience with Apple device support for both MacOS and iOS, including the JAMF environment
- Experience with Service Now a plus
- Basic understanding of network routing, switching and firewall concepts.